Schematic diagram of the IL-6/JAK/STAT3 signaling pathway activation in mouse liver macrophages. IRs, inhibitory receptors (IRs); ICIs, immune checkpoint inhibitors; IL-6, interleukin-6; ALT, alanine ...
Leveraging advanced spatial proteomics, scientists have identified the JAK/STAT pathway as a critical target for treating toxic epidermal necrolysis, offering new hope for patients with this ...
Brain Network Disorders review highlights role of JAK2 pathway in worsening ischemic stroke outcomes
Ischemic stroke is a major cause of death and disability, caused by a sudden loss of oxygen supply to the brain due to blocked blood vessels. Recanalization treatments such as intravenous thrombolysis ...
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