Chronic kidney diseases affect more than 10% of the world’s population, and most cases arise from disorders of the kidney’s filtration barrier, which is located within a million microvascular units ...

Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries — small blood vessels that regulate the movement of ions, water, and metabolites while maintaining ...

Insights into the role of ADGRF5 aids the understanding of glomerular disorders and significantly contributes to the advancement of future research." Unlocking the novel functions of the ADGRF5 ...

Microalbuminuria is significant both as the earliest stage of diabetic nephropathy and as an independent cardiovascular risk factor in nondiabetic subjects, in whom it is associated with insulin ...

Translational medicine researchers used the Mimetas® human kidney glomerulus-on-a-chip to investigate potential pharmaceutical interventions for patients with a severe kidney disease called focal ...

No therapies currently exist that can halt the progression of chronic kidney disease in children or restore the ability of kidney cells to filter blood. Recently, researchers at the GOFARR Laboratory ...

Cells expressing PAX8 (nucleus, red) considered podocyte precursors, line the outer Bowman’s capsule. Activated during the low salt-fasting mimicking diet (LS-FMD), the cells migrate and ...