The properties of the blood-brain barrier serve a vital protective role, but they also keep drugs from reaching the organ. Big pharmaceutical companies have been making deals for technologies that ...
Researchers identified a key molecule that highlights how the immune system is linked to the release of dopamine.
Worldwide, more than 55 million people suffer from dementia caused by Alzheimer's disease (AD) and other conditions that destroy cells in the brain and nervous system. While there is no treatment to ...
Fortress, filter, and gatekeeper: New insights into how the blood-brain barrier safeguards the brain
In a recent primer paper published in the journal Current Biology, researchers elucidated the structure and function of the blood-brain barrier (BBB). It highlights the BBB as a complex, dynamic ...
Days after JCR Pharmaceuticals signed a deal with AstraZeneca’s rare disease unit, the Japanese biopharma has secured a $555 million biobucks pact with Alzheimer’s-focused Acumen Pharmaceuticals. The ...
Roche may have been exploring ways to shuttle drugs to the brain for well over a decade, but that’s not stopping the pharma from handing $55 million to Manifold Bio for a fresh route through the blood ...
A common gastrointestinal cancer drug that crosses the blood-brain barrier showed promise in patients with aggressive high-grade gliomas. For avapritinib to be effective against HGGs, it would need to ...
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