The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

Bernd Rieger is in the Department of Imaging Physics, Faculty of Applied Sciences, Delft University of Technology, Delft 2628 CJ, the Netherlands. Enya S. Berrevoets is in the Department of Imaging ...

A team of Yale researchers discovered how a protein called Ndc1 coordinates nuclear pore and envelope assembly after cell division, an important component of understanding how cell nuclei change in ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Researchers have developed a new mathematical technique to begin to understand how a cell's nucleus is organized. They hope this understanding will expose vulnerabilities that can be targeted to ...

Scientists have uncovered how a newly discovered gene, NEK1, in which mutations have been linked to ALS cases, disrupts the function of the motor neuron and causes it to degenerate and die. The viral ...

Because viruses have to hijack someone else’s cell to replicate, they’ve gotten very good at it—inventing all sorts of tricks. A new study from two University of Chicago scientists has revealed how ...