Mathematicalmodels of cardiac action potentials have become increasingly important in the study of heart disease and pharmacology, but concerns linger over their robustness during long periods of ...

The zebrafish has emerged as a robust vertebrate model for studying cardiac electrophysiology and pharmacology, owing to its genetic tractability, optical transparency during early stages, and ...

An arrhythmia (also termed cardiac dysrhythmia) is described as an irregular heartbeat caused by aberrant electrical activity in the heart. There are multiple categories of arrhythmia, each of which ...

Novel pharmaceutical discovery and development is an expensive, difficult, and inefficient process, primarily due to the lack of models that accurately present the appropriate condition or that ...